SCOPe 2.06: Domain d3kfja_: 3kfj A:

Lineage for d3kfja_ (3kfj A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55564] (35 PDB entries)

8. Domain d3kfja_: 3kfj A: [179335]
   automated match to d1fhsa_
   complexed with cl, mg, yen

Details for d3kfja_

PDB Entry: 3kfj, 2.02 Å

PDB Description: Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-E-N-NH2 Tripeptide Mimic

PDB Compounds: (A:) Growth factor receptor-bound protein 2

SCOPe Domain Sequences for d3kfja_:

Sequence; same for both SEQRES and ATOM records:

>d3kfja_ d.93.1.1 (A:) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
kphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdga
gkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvp

Timeline for d3kfja_:

• d3kfja_ first appeared in SCOPe 2.01
  
• d3kfja_ appears in SCOPe 2.05
  
• d3kfja_ appears in SCOPe 2.07
  
• d3kfja_ appears in the current release, SCOPe 2.08