SCOPe 2.08: Domain d3kdtb1: 3kdt B:196-468

Lineage for d3kdtb1 (3kdt B:196-468)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69110] (30 PDB entries)

8. Domain d3kdtb1: 3kdt B:196-468 [179295]
   Other proteins in same PDB: d3kdtb2
   automated match to d1i7ga_
   protein/DNA complex; complexed with 7ha

Details for d3kdtb1

PDB Entry: 3kdt, 2.7 Å

PDB Description: Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine

PDB Compounds: (B:) Peroxisome proliferator-activated receptor alpha

SCOPe Domain Sequences for d3kdtb1:

Sequence, based on SEQRES records:

>d3kdtb1 a.123.1.1 (B:196-468) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
edsetadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlv
aklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvye
aifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdi
slfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrq
lvtehaqlvqiikktesdaalhpllqeiyrdmy

Sequence, based on observed residues (ATOM records):

>d3kdtb1 a.123.1.1 (B:196-468) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
edsetadlkslakriyeaylknfnmnkvkarvilsgkannppfvihdmetlcmaektlvv
angiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifa
mlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfv
aaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvte
haqlvqiikktesdaalhpllqeiyrdmy

Timeline for d3kdtb1:

• d3kdtb1 first appeared in SCOPe 2.01, called d3kdtb_
  
• d3kdtb1 appears in SCOPe 2.07