SCOPe 2.08: Domain d3kbza_: 3kbz A:

Lineage for d3kbza_ (3kbz A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.7: Carbohydrate phosphatase [56654] (1 superfamily)
   N-terminal domain is an alpha+beta, C-terminal domain is an alpha/beta with mixed beta-sheet

4. Superfamily e.7.1: Carbohydrate phosphatase [56655] (3 families)

5. Family e.7.1.1: Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (7 proteins)

6. Protein Fructose-1,6-bisphosphatase [56657] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56659] (9 PDB entries)

8. Domain d3kbza_: 3kbz A: [179248]
   automated match to d1ftaa_
   complexed with 2t4

Details for d3kbza_

PDB Entry: 3kbz, 2.45 Å

PDB Description: crystal structure of human liver fbpase in complex with tricyclic inhibitor 6

PDB Compounds: (A:) Fructose-1,6-bisphosphatase 1

SCOPe Domain Sequences for d3kbza_:

Sequence, based on SEQRES records:

>d3kbza_ e.7.1.1 (A:) Fructose-1,6-bisphosphatase {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagstnvtgd
qvkkldvlsndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidc
lvsvgtifgiyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldp
aigefilvdkdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsm
vadvhrtlvyggiflypankkspngklrllyecnpmayvmekaggmattgkeavldvipt
dihqrapvilgspddvleflkvyekhs

Sequence, based on observed residues (ATOM records):

>d3kbza_ e.7.1.1 (A:) Fructose-1,6-bisphosphatase {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagvkkldvl
sndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidclvsvgtif
giyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldpaigefilv
dkdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsmvadvhrtl
vyggiflypankkspngklrllyecnpmayvmekaggmattgkeavldviptdihqrapv
ilgspddvleflkvyekhs

Timeline for d3kbza_:

• d3kbza_ first appeared in SCOPe 2.01
  
• d3kbza_ appears in SCOPe 2.07