SCOPe 2.06: Domain d3k22a_: 3k22 A:

Lineage for d3k22a_ (3k22 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d3k22a_: 3k22 A: [178972]
   automated match to d1m2za_
   complexed with jzr, jzs

Details for d3k22a_

PDB Entry: 3k22, 2.1 Å

PDB Description: glucocorticoid receptor with bound alaninamide 10 with tif2 peptide

PDB Compounds: (A:) Glucocorticoid receptor

SCOPe Domain Sequences for d3k22a_:

Sequence, based on SEQRES records:

>d3k22a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfr
nlhlddqmtllqyswmylmafalgwrsyrqssanllcfapdliineqrmtlpgmydqckh
mlyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivkre
gnssqnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkys
ngnikkllfhq

Sequence, based on observed residues (ATOM records):

>d3k22a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfr
nlhlddqmtllqyswmylmafalgwrsyrqsanllcfapdliineqrmtlpgmydqckhm
lyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivkreg
nssqnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysn
gnikkllfhq

Timeline for d3k22a_:

• d3k22a_ first appeared in SCOPe 2.01
  
• d3k22a_ appears in SCOPe 2.05
  
• d3k22a_ appears in SCOPe 2.07
  
• d3k22a_ appears in the current release, SCOPe 2.08