SCOPe 2.06: Domain d3isjb_: 3isj B:

Lineage for d3isjb_ (3isj B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.4: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63976] (2 proteins)
   contains C-terminal subdomain similar to one structural repeat of the Creatinase/aminopeptidase family
   automatically mapped to Pfam PF02569

6. Protein Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63977] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [89615] (48 PDB entries)

8. Domain d3isjb_: 3isj B: [178592]
   automated match to d1n2ga_
   complexed with a8d, eoh, gol, so4

Details for d3isjb_

PDB Entry: 3isj, 2.2 Å

PDB Description: crystal structure of pantothenate synthetase from mycobacterium tuberculosis in complex with 5-methoxy-n-(methylsulfonyl)-1h-indole- 2-carboxamide

PDB Compounds: (B:) Pantothenate synthetase

SCOPe Domain Sequences for d3isjb_:

Sequence, based on SEQRES records:

>d3isjb_ c.26.1.4 (B:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
aipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsv
vvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqpg
plaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvav
vgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravlda
apgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigt

Sequence, based on observed residues (ATOM records):

>d3isjb_ c.26.1.4 (B:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
aipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsv
vvvsifvnpmqfprtpdddlaqlraegveiaftpttaamypdglrttvqpgplaaelegg
prpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvgvptvrea
dglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaapgvavdyl
elrdiglgpmplngsgrllvaarlgttrlldniaieigt

Timeline for d3isjb_:

• d3isjb_ first appeared in SCOPe 2.01
  
• d3isjb_ appears in SCOPe 2.05
  
• d3isjb_ appears in SCOPe 2.07
  
• d3isjb_ appears in the current release, SCOPe 2.08