SCOPe 2.05: Domain d3ipya_: 3ipy A:

Lineage for d3ipya_ (3ipy A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Deoxycytidine kinase [89657] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89658] (41 PDB entries)

8. Domain d3ipya_: 3ipy A: [178515]
   automated match to d1p5zb_
   complexed with b87, mlt

Details for d3ipya_

PDB Entry: 3ipy, 2.54 Å

PDB Description: X-Ray structure of Human Deoxycytidine Kinase in complex with an inhibitor

PDB Compounds: (A:) Deoxycytidine kinase

SCOPe Domain Sequences for d3ipya_:

Sequence, based on SEQRES records:

>d3ipya_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstqdefeeltmsqkngg
nvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifas
nlyesecmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqg
ipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflst
l

Sequence, based on observed residues (ATOM records):

>d3ipya_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnnggnvlqmmyekperwsft
fqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnetewtiy
qdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykhesw
llhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

Timeline for d3ipya_:

• d3ipya_ first appeared in SCOPe 2.01
  
• d3ipya_ appears in SCOPe 2.04
  
• d3ipya_ appears in SCOPe 2.06
  
• d3ipya_ appears in the current release, SCOPe 2.08