SCOPe 2.08: Domain d3ilza1: 3ilz A:148-410

Lineage for d3ilza1 (3ilz A:148-410)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Thyroid hormone receptor alpha1 (TR-alpha1) [48532] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88962] (5 PDB entries)

8. Domain d3ilza1: 3ilz A:148-410 [178392]
   Other proteins in same PDB: d3ilza2
   automated match to d1nava_
   complexed with b72

Details for d3ilza1

PDB Entry: 3ilz, 1.85 Å

PDB Description: Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group

PDB Compounds: (A:) Thyroid hormone receptor, alpha isoform 1 variant

SCOPe Domain Sequences for d3ilza1:

Sequence; same for both SEQRES and ATOM records:

>d3ilza1 a.123.1.1 (A:148-410) Thyroid hormone receptor alpha1 (TR-alpha1) {Human (Homo sapiens) [TaxId: 9606]}
eemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivsmpdg
dkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslraavry
dpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavllmst
drsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachasrflh
mkvecptelfpplflevfedqev

Timeline for d3ilza1:

• d3ilza1 first appeared in SCOPe 2.01, called d3ilza_
  
• d3ilza1 appears in SCOPe 2.07