SCOPe 2.04: Domain d3ic0c_: 3ic0 C:

Lineage for d3ic0c_ (3ic0 C:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.1: Globin-like [46457] (2 superfamilies)
   core: 6 helices; folded leaf, partly opened

4. Superfamily a.1.1: Globin-like [46458] (5 families)

5. Family a.1.1.2: Globins [46463] (27 proteins)
   Heme-binding protein

6. Protein Hemoglobin, alpha-chain [46486] (23 species)

7. Species Human (Homo sapiens) [TaxId:9606] [46487] (224 PDB entries)
   Uniprot P69905 P01922 P01934 P01935

8. Domain d3ic0c_: 3ic0 C: [178232]
   Other proteins in same PDB: d3ic0b_, d3ic0d_
   automated match to d1a00a_
   complexed with b77, hem, oxy, so4

Details for d3ic0c_

PDB Entry: 3ic0, 1.8 Å

PDB Description: crystal structure of liganded hemoglobin in complex with a potent antisickling agent, inn-298

PDB Compounds: (C:) Hemoglobin subunit alpha

SCOPe Domain Sequences for d3ic0c_:

Sequence; same for both SEQRES and ATOM records:

>d3ic0c_ a.1.1.2 (C:) Hemoglobin, alpha-chain {Human (Homo sapiens) [TaxId: 9606]}
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

Timeline for d3ic0c_:

• d3ic0c_ first appeared in SCOPe 2.01
  
• d3ic0c_ appears in SCOPe 2.03
  
• d3ic0c_ appears in SCOPe 2.05
  
• d3ic0c_ appears in the current release, SCOPe 2.08