SCOPe 2.01: Domain d3iaza1: 3iaz A:342-685

Lineage for d3iaza1 (3iaz A:342-685)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.94: Periplasmic binding protein-like II [53849] (1 superfamily)
   consists of two similar intertwined domain with 3 layers (a/b/a) each: duplication
   mixed beta-sheet of 5 strands, order 21354; strand 5 is antiparallel to the rest

4. Superfamily c.94.1: Periplasmic binding protein-like II [53850] (4 families)
   Similar in architecture to the superfamily I but partly differs in topology

5. Family c.94.1.2: Transferrin [53888] (4 proteins)
   further duplication: composed of two two-domain lobes

6. Protein Lactoferrin [53889] (6 species)

7. Species Cow (Bos taurus) [TaxId:9913] [53891] (44 PDB entries)

8. Domain d3iaza1: 3iaz A:342-685 [178217]
   automatically matched to d1nkxa_
   complexed with ain, co3, eoh, fe, so4, zn

Details for d3iaza1

PDB Entry: 3iaz, 2 Å

PDB Description: structural basis of the prevention of nsaid-induced damage of the gastrointestinal tract by c-terminal half (c-lobe) of bovine colostrum protein lactoferrin: binding and structural studies of the c-lobe complex with aspirin

PDB Compounds: (A:) lactotransferrin

SCOPe Domain Sequences for d3iaza1:

Sequence, based on SEQRES records:

>d3iaza1 c.94.1.2 (A:342-685) Lactoferrin {Cow (Bos taurus) [TaxId: 9913]}
ytrvvwcavgpeeqkkcqqwsqqsgqnvtcatasttddcivlvlkgeadalnldggyiyt
agkcglvpvlaenrksskhssldcvlrptegylavavvkkanegltwnslkdkkschtav
drtagwnipmglivnqtgscafdeffsqscapgadpksrlcalcagddqgldkcvpnske
kyygytgafrclaedvgdvafvkndtvwentngestadwaknlkredfrllcldgtrkpv
teaqschlavapnhavvsrsdraahveqvllhqqalfgkngkncpdkfclfksetknllf
ndnteclaklggrptyeeylgteyvtaianlkkcstsplleaca

Sequence, based on observed residues (ATOM records):

>d3iaza1 c.94.1.2 (A:342-685) Lactoferrin {Cow (Bos taurus) [TaxId: 9913]}
ytrvvwcavgpeeqkkcqqwsqqsgqnvtcatasttddcivlvlkgeadalnldggyiyt
agkcglvpvlaenrksskhssldcvlrptegylavavvkkanegltwnslkdkkschtav
drtagwnipmglivnqtgscafdeffsqscapgadpksrlcalcagddqgldkcvpnske
kyygytgafrclaedvgdvafvkndtvwentngestadwaknlkredfrllcldgtrkpv
teaqschlavapnhavvsrsdraahveqvllhqqalfgkngkncpdkfclfksetknllf
ndnteclaklggrptyeeylgteyvtaianlkkcsleaca

Timeline for d3iaza1:

• d3iaza1 is new in SCOPe 2.01-stable
  
• d3iaza1 appears in SCOPe 2.02
  
• d3iaza1 appears in the current release, SCOPe 2.08, called d3iaza_