SCOPe 2.07: Domain d3iara1: 3iar A:5-363

Lineage for d3iara1 (3iar A:5-363)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.1: Adenosine/AMP deaminase [51557] (3 proteins)

6. Protein Adenosine deaminase (ADA) [51558] (4 species)
   Common fold covers the whole protein structure

7. Species Human (Homo sapiens) [TaxId:9606] [224876] (1 PDB entry)

8. Domain d3iara1: 3iar A:5-363 [178216]
   Other proteins in same PDB: d3iara2
   automated match to d1w1ie_
   complexed with 3d1, gol, ni, no3

Details for d3iara1

PDB Entry: 3iar, 1.52 Å

PDB Description: The crystal structure of human adenosine deaminase

PDB Compounds: (A:) adenosine deaminase

SCOPe Domain Sequences for d3iara1:

Sequence; same for both SEQRES and ATOM records:

>d3iara1 c.1.9.1 (A:5-363) Adenosine deaminase (ADA) {Human (Homo sapiens) [TaxId: 9606]}
pafdkpkvelhvhldgsikpetilyygrrrgialpantaegllnvigmdkpltlpdflak
fdyympaiagcreaikriayefvemkakegvvyvevrysphllanskvepipwnqaegdl
tpdevvalvgqglqegerdfgvkarsilccmrhqpnwspkvvelckkyqqqtvvaidlag
detipgssllpghvqayqeavksgihrtvhagevgsaevvkeavdilkterlghgyhtle
dqalynrlrqenmhfeicpwssyltgawkpdtehavirlkndqanyslntddplifkstl
dtdyqmtkrdmgfteeefkrlninaakssflpedekrelldllykaygmppsasagqnl

Timeline for d3iara1:

• d3iara1 first appeared in SCOPe 2.01, called d3iara_
  
• d3iara1 appears in SCOPe 2.06
  
• d3iara1 appears in the current release, SCOPe 2.08