Lineage for d3i8ax_ (3i8a X:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477974Family c.71.1.0: automated matches [191485] (1 protein)
    not a true family
  6. 2477975Protein automated matches [190777] (22 species)
    not a true protein
  7. 2478176Species Staphylococcus aureus [TaxId:1280] [188848] (9 PDB entries)
  8. 2478191Domain d3i8ax_: 3i8a X: [178143]
    automated match to d1dhja_
    complexed with n22, ndp

Details for d3i8ax_

PDB Entry: 3i8a (more details), 2.41 Å

PDB Description: Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)
PDB Compounds: (X:) dihydrofolate reductase

SCOPe Domain Sequences for d3i8ax_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3i8ax_ c.71.1.0 (X:) automated matches {Staphylococcus aureus [TaxId: 1280]}

SCOPe Domain Coordinates for d3i8ax_:

Click to download the PDB-style file with coordinates for d3i8ax_.
(The format of our PDB-style files is described here.)

Timeline for d3i8ax_: