SCOPe 2.08: Domain d3hzfa1: 3hzf A:148-407

Lineage for d3hzfa1 (3hzf A:148-407)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d3hzfa1: 3hzf A:148-407 [177962]
   Other proteins in same PDB: d3hzfa2
   automated match to d1nava_
   complexed with b72

Details for d3hzfa1

PDB Entry: 3hzf, 2.5 Å

PDB Description: Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group

PDB Compounds: (A:) Thyroid hormone receptor, alpha isoform 1 variant

SCOPe Domain Sequences for d3hzfa1:

Sequence; same for both SEQRES and ATOM records:

>d3hzfa1 a.123.1.1 (A:148-407) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivsmpdg
dkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslraavry
dpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavllmst
drsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachasrflh
mkvecptelfpplflevfed

Timeline for d3hzfa1:

• d3hzfa1 first appeared in SCOPe 2.01, called d3hzfa_
  
• d3hzfa1 appears in SCOPe 2.07