SCOPe 2.04: Domain d3hxfb_: 3hxf B:

Lineage for d3hxfb_ (3hxf B:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.3: Protein prenyltransferases [48246] (3 proteins)

6. Protein Rab geranylgeranyltransferase, beta subunit [48249] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48250] (21 PDB entries)

8. Domain d3hxfb_: 3hxf B: [177902]
   automated match to d1dceb_
   complexed with bd9, ca, zn

Details for d3hxfb_

PDB Entry: 3hxf, 1.9 Å

PDB Description: engineered rabggtase in complex with a peptidomimetic inhibitor (compound 32)

PDB Compounds: (B:) Geranylgeranyl transferase type-2 subunit beta

SCOPe Domain Sequences for d3hxfb_:

Sequence, based on SEQRES records:

>d3hxfb_ a.102.4.3 (B:) Rab geranylgeranyltransferase, beta subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
qkdvtiksdapdtlllekhadyiasygskkddyeycmseylrmsgvywgltvmdlmgqlh
rmnkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvq
slqkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcr
pgseshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcysww
vlaslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgee
qikpvspvfcmpeevlqrvnvqpelv

Sequence, based on observed residues (ATOM records):

>d3hxfb_ a.102.4.3 (B:) Rab geranylgeranyltransferase, beta subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
qkdvtiksdapdtlllekhadyiasygsyeycmseylrmsgvywgltvmdlmgqlhrmnk
eeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqslqk
edgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpgse
shagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvlas
lkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqikp
vspvfcmpeevlqrvnvqpelv

Timeline for d3hxfb_:

• d3hxfb_ first appeared in SCOPe 2.01
  
• d3hxfb_ appears in SCOPe 2.03
  
• d3hxfb_ appears in SCOPe 2.05
  
• d3hxfb_ appears in the current release, SCOPe 2.08