SCOPe 2.05: Domain d3hxeb_: 3hxe B:

Lineage for d3hxeb_ (3hxe B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.3: Protein prenyltransferases [48246] (3 proteins)

6. Protein Rab geranylgeranyltransferase, beta subunit [48249] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48250] (21 PDB entries)

8. Domain d3hxeb_: 3hxe B: [177901]
   automated match to d1dceb_
   complexed with bd8, ca, zn

Details for d3hxeb_

PDB Entry: 3hxe, 1.95 Å

PDB Description: engineered rabggtase in complex with a peptidomimetic inhibitor (compound 37)

PDB Compounds: (B:) Geranylgeranyl transferase type-2 subunit beta

SCOPe Domain Sequences for d3hxeb_:

Sequence, based on SEQRES records:

>d3hxeb_ a.102.4.3 (B:) Rab geranylgeranyltransferase, beta subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
qkdvtiksdapdtlllekhadyiasygskkddyeycmseylrmsgvywgltvmdlmgqlh
rmnkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvq
slqkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcr
pgseshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcysww
vlaslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgee
qikpvspvfcmpeevlqrvnvqpelvs

Sequence, based on observed residues (ATOM records):

>d3hxeb_ a.102.4.3 (B:) Rab geranylgeranyltransferase, beta subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
qkdvtiksdapdtlllekhadyiasygsdyeycmseylrmsgvywgltvmdlmgqlhrmn
keeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqslq
kedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpgs
eshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvla
slkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqik
pvspvfcmpeevlqrvnvqpelvs

Timeline for d3hxeb_:

• d3hxeb_ first appeared in SCOPe 2.01
  
• d3hxeb_ appears in SCOPe 2.04
  
• d3hxeb_ appears in SCOPe 2.06
  
• d3hxeb_ appears in the current release, SCOPe 2.08