SCOPe 2.07: Domain d3hpda_: 3hpd A:

Lineage for d3hpda_ (3hpd A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.1: Ribokinase-like [53613] (6 families)
   has extra strand located between strands 2 and 3

5. Family c.72.1.2: Thiamin biosynthesis kinases [53620] (2 protein domains)

6. Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) [53621] (2 species)

7. Species Pyrococcus horikoshii [TaxId:53953] [102637] (2 PDB entries)

8. Domain d3hpda_: 3hpd A: [177751]
   complexed with po4

Details for d3hpda_

PDB Entry: 3hpd, 1.85 Å

PDB Description: Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3

PDB Compounds: (A:) hydroxyethylthiazole kinase

SCOPe Domain Sequences for d3hpda_:

Sequence, based on SEQRES records:

>d3hpda_ c.72.1.2 (A:) Hydroxyethylthiazole kinase (THZ kinase, ThiK) {Pyrococcus horikoshii [TaxId: 53953]}
mkfiiealkrvrerrplvhnitnfvvmnttanallalgaspvmahaeeeleemirladav
vinigtldsgwrrsmvkateianelgkpivldpvgagatkfrtrvsleilsrgvdvlkgn
fgeisallgeegktrgvdsleygeeeakkltmnaarefnttvavtgavdyvsdgrrtfav
ynghellgrvtgtgcmvaaltgafvavteplkattsalvtfgiaaekayeeakypgsfhv
klydwlyrinenvirtyakvreve

Sequence, based on observed residues (ATOM records):

>d3hpda_ c.72.1.2 (A:) Hydroxyethylthiazole kinase (THZ kinase, ThiK) {Pyrococcus horikoshii [TaxId: 53953]}
mkfiiealkrvrerrplvhnitnfvvmnttanallalgaspvmahaeeeleemirladav
vinigtldsgwrrsmvkateianelgkpivldpvgagatkfrtrvsleilsrgvdvlkgn
fgeisallgeeggeeeakkltmnaarefnttvavtgavdyvsdgrrtfavynghellgrv
tgtgcmvaaltgafvavteplkattsalvtfgiaaekayeeakypgsfhvklydwlyrin
envirtyakvreve

Timeline for d3hpda_:

• d3hpda_ first appeared in SCOPe 2.01
  
• d3hpda_ appears in SCOPe 2.06