Lineage for d3hd3a_ (3hd3 A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2154577Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2154578Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2154579Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2154783Protein Cruzain [54020] (1 species)
  7. 2154784Species Trypanosoma cruzi [TaxId:5693] [54021] (25 PDB entries)
  8. 2154797Domain d3hd3a_: 3hd3 A: [177400]
    automated match to d1ewla_
    complexed with 25b, edo, eoh, peg, so4

Details for d3hd3a_

PDB Entry: 3hd3 (more details), 1.75 Å

PDB Description: High resolution crystal structure of cruzain bound to the vinyl sulfone inhibitor SMDC-256047
PDB Compounds: (A:) Cruzipain

SCOPe Domain Sequences for d3hd3a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3hd3a_ d.3.1.1 (A:) Cruzain {Trypanosoma cruzi [TaxId: 5693]}

SCOPe Domain Coordinates for d3hd3a_:

Click to download the PDB-style file with coordinates for d3hd3a_.
(The format of our PDB-style files is described here.)

Timeline for d3hd3a_: