Lineage for d3hc8a_ (3hc8 A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2014835Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2014836Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2014926Family a.211.1.2: PDEase [48548] (7 protein domains)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 2015191Protein automated matches [190370] (1 species)
    not a true protein
  7. 2015192Species Human (Homo sapiens) [TaxId:9606] [187208] (25 PDB entries)
  8. 2015194Domain d3hc8a_: 3hc8 A: [177364]
    automated match to d1t9sa_
    complexed with mg, pd4, zn

Details for d3hc8a_

PDB Entry: 3hc8 (more details), 1.79 Å

PDB Description: Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System.
PDB Compounds: (A:) cGMP-specific 3',5'-cyclic phosphodiesterase, cAMP-specific 3',5'-cyclic phosphodiesterase 4B

SCOPe Domain Sequences for d3hc8a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3hc8a_ a.211.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3hc8a_:

Click to download the PDB-style file with coordinates for d3hc8a_.
(The format of our PDB-style files is described here.)

Timeline for d3hc8a_: