SCOPe 2.06: Domain d3h52a1: 3h52 A:528-776

Lineage for d3h52a1 (3h52 A:528-776)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d3h52a1: 3h52 A:528-776 [177189]
   Other proteins in same PDB: d3h52a2, d3h52c2
   automated match to d1m2za_
   complexed with 486, gol

Details for d3h52a1

PDB Entry: 3h52, 2.8 Å

PDB Description: crystal structure of the antagonist form of human glucocorticoid receptor

PDB Compounds: (A:) Glucocorticoid receptor

SCOPe Domain Sequences for d3h52a1:

Sequence, based on SEQRES records:

>d3h52a1 a.123.1.1 (A:528-776) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfrnl
hlddqmtllqyswmslmafalgwrsyrqssanllcfapdliineqrmtlpdmydqckhml
yvsselhrlqvsyeeylcmktllllssvpkdglksqalfdairmtyikelgkaivkregn
ssqnsqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysng
nikkllfhq

Sequence, based on observed residues (ATOM records):

>d3h52a1 a.123.1.1 (A:528-776) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfrnl
hlddqmtllqyswmslmafalgwrsyrqssanllcfapdliineqrmtlpdmydqckhml
yvsselhrlqvsyeeylcmktllllssvpkdglksqalfdairmtyikelgkaivkregn
ssqnsqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipgnikk
llfhq

Timeline for d3h52a1:

• d3h52a1 first appeared in SCOPe 2.01, called d3h52a_
  
• d3h52a1 was called d3h52a_ in SCOPe 2.05
  
• d3h52a1 appears in SCOPe 2.07
  
• d3h52a1 appears in the current release, SCOPe 2.08