SCOPe 2.06: Domain d3gwva_: 3gwv A:

Lineage for d3gwva_ (3gwv A:)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (1 family)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein automated matches [190994] (2 species)
   not a true protein

7. Species Aquifex aeolicus [TaxId:224324] [188879] (3 PDB entries)

8. Domain d3gwva_: 3gwv A: [177063]
   automated match to d2a65a1
   complexed with leu, na, rfx

Details for d3gwva_

PDB Entry: 3gwv, 2.35 Å

PDB Description: leucine transporter leut in complex with r-fluoxetine

PDB Compounds: (A:) Transporter

SCOPe Domain Sequences for d3gwva_:

Sequence, based on SEQRES records:

>d3gwva_ f.54.1.1 (A:) automated matches {Aquifex aeolicus [TaxId: 224324]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsili
rgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvw
iaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaava
ffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmi
afledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiff
wifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvw
itrfyiiglflfltflvflaerrrnh

Sequence, based on observed residues (ATOM records):

>d3gwva_ f.54.1.1 (A:) automated matches {Aquifex aeolicus [TaxId: 224324]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpeppptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirg
iskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwia
avgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaff
gvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiaf
ledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwi
fgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyithwtvwitrfyiig
lflfltflvflaerrrnh

Timeline for d3gwva_:

• d3gwva_ first appeared in SCOPe 2.01
  
• d3gwva_ appears in SCOPe 2.05
  
• d3gwva_ appears in SCOPe 2.07
  
• d3gwva_ appears in the current release, SCOPe 2.08