SCOPe 2.07: Domain d3gwua1: 3gwu A:5-513

Lineage for d3gwua1 (3gwu A:5-513)

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (1 family)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein automated matches [190994] (2 species)
   not a true protein

7. Species Aquifex aeolicus [TaxId:224324] [188879] (3 PDB entries)

8. Domain d3gwua1: 3gwu A:5-513 [177062]
   Other proteins in same PDB: d3gwua2
   automated match to d2a65a1
   complexed with leu, na, sre

Details for d3gwua1

PDB Entry: 3gwu, 2.14 Å

PDB Description: leucine transporter leut in complex with sertraline

PDB Compounds: (A:) Transporter

SCOPe Domain Sequences for d3gwua1:

Sequence, based on SEQRES records:

>d3gwua1 f.54.1.1 (A:5-513) automated matches {Aquifex aeolicus [TaxId: 224324]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsili
rgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvw
iaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaava
ffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmi
afledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiff
wifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvw
itrfyiiglflfltflvflaerrrnhesa

Sequence, based on observed residues (ATOM records):

>d3gwua1 f.54.1.1 (A:5-513) automated matches {Aquifex aeolicus [TaxId: 224324]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpeppptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirg
iskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwia
avgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaff
gvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiaf
ledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwi
fgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwit
rfyiiglflfltflvflaerrrnhesa

Timeline for d3gwua1:

• d3gwua1 first appeared in SCOPe 2.01, called d3gwua_
  
• d3gwua1 appears in SCOPe 2.06
  
• d3gwua1 appears in the current release, SCOPe 2.08