SCOPe 2.07: Domain d3gn8a_: 3gn8 A:

Lineage for d3gn8a_ (3gn8 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d3gn8a_: 3gn8 A: [176774]
   automated match to d1m2za_
   complexed with dex

Details for d3gn8a_

PDB Entry: 3gn8, 2.5 Å

PDB Description: X-ray Crystal Structure of AncGR2 in Complex with Dexamethasone

PDB Compounds: (A:) Glucocorticoid receptor 2

SCOPe Domain Sequences for d3gn8a_:

Sequence; same for both SEQRES and ATOM records:

>d3gn8a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aptlislleviepevlysgydstlpdtstrlmstlnrlggrqvvsavkwakalpgfrnlh
lddqmtllqyswmslmafslgwrsykqsngnmlcfapdlvineermqlpymydqcqqmlk
issefvrlqvsydeylcmkvllllstvpkdglksqavfdeirmtyikelgkaivkregns
sqnwqrfyqltklldsmhemvggllqfcfytfvnkslsvefpemlaeiisnqlpkfkags
vkpllfhqk

Timeline for d3gn8a_:

• d3gn8a_ first appeared in SCOPe 2.01
  
• d3gn8a_ appears in SCOPe 2.06
  
• d3gn8a_ appears in the current release, SCOPe 2.08, called d3gn8a1