SCOPe 2.01: Domain d3gepa_: 3gep A:

Lineage for d3gepa_ (3gep A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.61: PRTase-like [53270] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.61.1: PRTase-like [53271] (3 families)

5. Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 proteins)

6. Protein Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53284] (7 PDB entries)

8. Domain d3gepa_: 3gep A: [176581]
   automated match to d1bzya_
   complexed with 24h

Details for d3gepa_

PDB Entry: 3gep, 2.6 Å

PDB Description: Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine

PDB Compounds: (A:) hypoxanthine-guanine phosphoribosyltransferase

SCOPe Domain Sequences for d3gepa_:

Sequence, based on SEQRES records:

>d3gepa_ c.61.1.1 (A:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
rspgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiv
alcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikviggddls
tltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfei
pdkfvvgyaldyneyfrdlnhvcvisetgkakyka

Sequence, based on observed residues (ATOM records):

>d3gepa_ c.61.1.1 (A:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
rspgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiv
alcvlkggykffadlldyikalnrnsdrsipmtvdfirlksdqstgdikviggddlstlt
gknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeipdk
fvvgyaldyneyfrdlnhvcvisetgkakyka

Timeline for d3gepa_:

• d3gepa_ is new in SCOPe 2.01-stable
  
• d3gepa_ appears in SCOPe 2.02
  
• d3gepa_ appears in the current release, SCOPe 2.08