SCOPe 2.06: Domain d3gcia_: 3gci A:

Lineage for d3gcia_ (3gci A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
   common core: 2 helices, disulfide-linked, and a calcium-binding loop

4. Superfamily a.133.1: Phospholipase A2, PLA2 [48619] (4 families)

5. Family a.133.1.2: Vertebrate phospholipase A2 [48623] (3 proteins)
   automatically mapped to Pfam PF00068

6. Protein Snake phospholipase A2 [48624] (38 species)

7. Species Andaman cobra (Naja sagittifera), isoform 4 [TaxId:195058] [89171] (14 PDB entries)
   Uniprot P60045 8-126 # ! yet another isoform, 98% identity

8. Domain d3gcia_: 3gci A: [176518]
   automated match to d1ln8a_
   complexed with ca

Details for d3gcia_

PDB Entry: 3gci, 2.04 Å

PDB Description: Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal Amyloid Beta Heptapeptide at 2 A Resolution

PDB Compounds: (A:) Phospholipase A2 isoform 3

SCOPe Domain Sequences for d3gcia_:

Sequence; same for both SEQRES and ATOM records:

>d3gcia_ a.133.1.2 (A:) Snake phospholipase A2 {Andaman cobra (Naja sagittifera), isoform 4 [TaxId: 195058]}
nlyqfknmiqctvpsrswadfadygcycgkggsgtpvddldrccqthdncyneaenisgc
rpkfktysyectqgtltckgdnnacaasvcdcdrlaaicfagapyndanynidlkarcn

Timeline for d3gcia_:

• d3gcia_ first appeared in SCOPe 2.01
  
• d3gcia_ appears in SCOPe 2.05
  
• d3gcia_ appears in SCOPe 2.07
  
• d3gcia_ appears in the current release, SCOPe 2.08