SCOPe 2.06: Domain d3gc9a_: 3gc9 A:

Lineage for d3gc9a_ (3gc9 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d3gc9a_: 3gc9 A: [176516]
   automated match to d1a9ua_
   complexed with b45, na, zn

Details for d3gc9a_

PDB Entry: 3gc9, 2.05 Å

PDB Description: the structure of p38beta c119s, c162s in complex with a dihydroquinazolinone inhibitor

PDB Compounds: (A:) Mitogen-activated protein kinase 11

SCOPe Domain Sequences for d3gc9a_:

Sequence, based on SEQRES records:

>d3gc9a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gpragfyrqelnktvwevpqrlqglrpvgsgaygsvcsaydarlrqkvavkklsrpfqsl
iharrtyrelrllkhlkhenviglldvftpatsiedfsevylvttlmgadlnnivksqal
sdehvqflvyqllrglkyihsagiihrdlkpsnvavnedselrildfglarqadeemtgy
vatrwyrapeimlnwmhynqtvdiwsvgcimaellqgkalfpgsdyidqlkrimevvgtp
spevlakissehartyiqslppmpqkdlssifrganplaidllgrmlvldsdqrvsaaea
lahayfsqyhdpedepeaepydesveakertleewkeltyqevlsf

Sequence, based on observed residues (ATOM records):

>d3gc9a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gpragfyrqelnktvwevpqrlqglrpvgsgaygsvcsaydarlrqkvavkklsrpfqsl
iharrtyrelrllkhlkhenviglldvftpatsiedfsevylvttlmgadlnnivksqal
sdehvqflvyqllrglkyihsagiihrdlkpsnvavnedselrildfglaatrwyrapei
mlnwmhynqtvdiwsvgcimaellqgkalfpgsdyidqlkrimevvgtpspevlakisse
hartyiqslppmpqkdlssifrganplaidllgrmlvldsdqrvsaaealahayfsqyhd
pedepeaepydesveakertleewkeltyqevlsf

Timeline for d3gc9a_:

• d3gc9a_ first appeared in SCOPe 2.01
  
• d3gc9a_ appears in SCOPe 2.05
  
• d3gc9a_ appears in SCOPe 2.07
  
• d3gc9a_ appears in the current release, SCOPe 2.08