SCOPe 2.08: Domain d3g9lx_: 3g9l X:

Lineage for d3g9lx_ (3g9l X:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-jun N-terminal kinase (jnk3s) [56137] (1 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56138] (50 PDB entries)

8. Domain d3g9lx_: 3g9l X: [176447]
   automated match to d1jnka_
   complexed with j67

Details for d3g9lx_

PDB Entry: 3g9l, 2.2 Å

PDB Description: jnk3 bound to (z)-1-((6-fluoro-4h-benzo[d][1,3]dioxin-8-yl)methyl)-3- (hydroxyimino)-4-styrylindolin-2-one

PDB Compounds: (X:) Mitogen-activated protein kinase 10

SCOPe Domain Sequences for d3g9lx_:

Sequence, based on SEQRES records:

>d3g9lx_ d.144.1.7 (X:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyvv
tryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpe
fmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpa
krisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmn

Sequence, based on observed residues (ATOM records):

>d3g9lx_ d.144.1.7 (X:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigivcaaydavldrnvaikklsrpfqnqthakrayr
elvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyll
yqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglsfmmtvtryyrapevilgmg
ykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyve
nrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyi
nvwydpaeveapppqiderehtieewkeliykevmn

Timeline for d3g9lx_:

• d3g9lx_ first appeared in SCOPe 2.01
  
• d3g9lx_ appears in SCOPe 2.07