SCOPe 2.05: Domain d3g5ma_: 3g5m A:

Lineage for d3g5ma_ (3g5m A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.5: Flavoproteins [52218] (9 families)

5. Family c.23.5.3: Quinone reductase [52235] (4 proteins)
   binds FAD

6. Protein Quinone reductase type 2 (menadione reductase) [52240] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52241] (53 PDB entries)

8. Domain d3g5ma_: 3g5m A: [176382]
   automated match to d1qr2a_
   complexed with fad, xm5, zn

Details for d3g5ma_

PDB Entry: 3g5m, 1.84 Å

PDB Description: Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory activity

PDB Compounds: (A:) Ribosyldihydronicotinamide dehydrogenase [quinone]

SCOPe Domain Sequences for d3g5ma_:

Sequence; same for both SEQRES and ATOM records:

>d3g5ma_ c.23.5.3 (A:) Quinone reductase type 2 (menadione reductase) {Human (Homo sapiens) [TaxId: 9606]}
agkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtls
npevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrvl
cqgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfcg
fkvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq

Timeline for d3g5ma_:

• d3g5ma_ first appeared in SCOPe 2.01
  
• d3g5ma_ appears in SCOPe 2.04
  
• d3g5ma_ appears in SCOPe 2.06
  
• d3g5ma_ appears in the current release, SCOPe 2.08