SCOPe 2.05: Domain d3fsia_: 3fsi A:

Lineage for d3fsia_ (3fsi A:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein automated matches [190211] (5 species)
   not a true protein

7. Species Moloney murine leukemia virus [TaxId:11801] [188900] (1 PDB entry)

8. Domain d3fsia_: 3fsi A: [176028]
   automated match to d1d0ea_
   protein/DNA complex; complexed with act, mwb

Details for d3fsia_

PDB Entry: 3fsi, 1.75 Å

PDB Description: crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino) diphenylamine bound to dna

PDB Compounds: (A:) Reverse transcriptase domain

SCOPe Domain Sequences for d3fsia_:

Sequence, based on SEQRES records:

>d3fsia_ e.8.1.2 (A:) automated matches {Moloney murine leukemia virus [TaxId: 11801]}
twlsdfpqawaetggmglavrqapliiplkatstpvsikqypmsqearlgikphiqrlld
qgilvpcqspwntpllpvkkpgtndyrpvqdlrevnkrvedihptvpnpynllsglppsh
qwytvldlkdaffclrlhptsqplfafewrdpemgisgqltwtrlpqgfknsptlfdeal
hrdladfriqhpdlillqyvddlllaatseldcqqgtrallqtlgnlgyrasakkaqicq
kqvkylgyllkegqr

Sequence, based on observed residues (ATOM records):

>d3fsia_ e.8.1.2 (A:) automated matches {Moloney murine leukemia virus [TaxId: 11801]}
twlsdfpqawaetggmglavrqapliiplkatstpvsikqypmsqearlgikphiqrlld
qgilvpcqspwntpllpvyrpvqdlrevnkrvedihptvpnpynllsglppshqwytvld
lkdaffclrlhptsqplfafewrdpemgisgqltwtrlpqgfknsptlfdealhrdladf
riqhpdlillqyvddlllaatseldcqqgtrallqtlgnlgyrasakkaqicqkqvkylg
yllkegqr

Timeline for d3fsia_:

• d3fsia_ first appeared in SCOPe 2.01
  
• d3fsia_ appears in SCOPe 2.04
  
• d3fsia_ appears in SCOPe 2.06
  
• d3fsia_ appears in the current release, SCOPe 2.08