Lineage for d3fqva_ (3fqv A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477974Family c.71.1.0: automated matches [191485] (1 protein)
    not a true family
  6. 2477975Protein automated matches [190777] (21 species)
    not a true protein
  7. 2478196Species Staphylococcus aureus [TaxId:273036] [188831] (12 PDB entries)
  8. 2478201Domain d3fqva_: 3fqv A: [175988]
    automated match to d1ddra_
    complexed with 11f, ndp; mutant

Details for d3fqva_

PDB Entry: 3fqv (more details), 1.85 Å

PDB Description: staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1- ynyl]-6-methylpyrimidine
PDB Compounds: (A:) Trimethoprim-sensitive dihydrofolate reductase

SCOPe Domain Sequences for d3fqva_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3fqva_ c.71.1.0 (A:) automated matches {Staphylococcus aureus [TaxId: 273036]}

SCOPe Domain Coordinates for d3fqva_:

Click to download the PDB-style file with coordinates for d3fqva_.
(The format of our PDB-style files is described here.)

Timeline for d3fqva_: