SCOPe 2.08: Domain d3fqkb1: 3fqk B:2-562

Lineage for d3fqkb1 (3fqk B:2-562)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus genotype 1b (isolate bk) [TaxId:11105] [188687] (17 PDB entries)

8. Domain d3fqkb1: 3fqk B:2-562 [175980]
   Other proteins in same PDB: d3fqka2, d3fqkb2
   automated match to d1nb4a_
   complexed with 79z

Details for d3fqkb1

PDB Entry: 3fqk, 2.2 Å

PDB Description: Hepatitis C virus polymerase NS5B (BK 1-570) with HCV-796 inhibitor

PDB Compounds: (B:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d3fqkb1:

Sequence, based on SEQRES records:

>d3fqkb1 e.8.1.4 (B:2-562) automated matches {Hepatitis C virus genotype 1b (isolate bk) [TaxId: 11105]}
msytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihs
vwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvst
lpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyq
ccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasa
acraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydle
litscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwa
rmilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspge
inrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipa
asrldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d3fqkb1 e.8.1.4 (B:2-562) automated matches {Hepatitis C virus genotype 1b (isolate bk) [TaxId: 11105]}
msytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihs
vwkdlledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqvv
mgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdla
pearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacraa
klqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydlelitsc
ssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilm
thffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrva
sclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipaasrld
lsgwfvagysggdiyh

Timeline for d3fqkb1:

• d3fqkb1 first appeared in SCOPe 2.01, called d3fqkb_
  
• d3fqkb1 appears in SCOPe 2.07