Lineage for d3fj6a_ (3fj6 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080000Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2080001Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 protein domains)
  6. 2080389Protein automated matches [190228] (18 species)
    not a true protein
  7. 2080395Species Human (Homo sapiens) [TaxId:9606] [187000] (8 PDB entries)
  8. 2080398Domain d3fj6a_: 3fj6 A: [175839]
    automated match to d1d3ga_
    complexed with act, cih, fmn, oro, so4

Details for d3fj6a_

PDB Entry: 3fj6 (more details), 1.8 Å

PDB Description: Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2
PDB Compounds: (A:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d3fj6a_:

Sequence, based on SEQRES records: (download)

>d3fj6a_ c.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpv
giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
vsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvv
kelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiig
vggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaiga
dhrr

Sequence, based on observed residues (ATOM records): (download)

>d3fj6a_ c.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllpfqdsdmlevrvlghkfrnpvgia
agfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshgls
vvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvss
pntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkel
gidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvgg
vssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhr
r

SCOPe Domain Coordinates for d3fj6a_:

Click to download the PDB-style file with coordinates for d3fj6a_.
(The format of our PDB-style files is described here.)

Timeline for d3fj6a_: