SCOPe 2.05: Domain d3fhya_: 3fhy A:

Lineage for d3fhya_ (3fhy A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.1: Ribokinase-like [53613] (6 families)
   has extra strand located between strands 2 and 3

5. Family c.72.1.5: PfkB-like kinase [82515] (3 proteins)
   includes a variety of carbohydrate and pyrimidine kinases

6. Protein automated matches [190479] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187406] (9 PDB entries)

8. Domain d3fhya_: 3fhy A: [175796]
   automated match to d1rfua_
   complexed with atp, mg, mpd, na, so4; mutant

Details for d3fhya_

PDB Entry: 3fhy, 2.3 Å

PDB Description: crystal structure of d235n mutant of human pyridoxal kinase

PDB Compounds: (A:) Pyridoxal kinase

SCOPe Domain Sequences for d3fhya_:

Sequence, based on SEQRES records:

>d3fhya_ c.72.1.5 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsdelq
elyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkwdge
gsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgpdtv
vitssdlpspqgsnylivlgsqrrrnpagsvvmerirmdirkvdavfvgtgnlfaamlla
wthkhpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdiedp
eivvqatvl

Sequence, based on observed residues (ATOM records):

>d3fhya_ c.72.1.5 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecrvlsiqshvirgyvgnraatfplqvlgfeidavnsvqfsnhtgyahwkgqvlnsdelq
elyeglrlnnmnkydyvltgytrdksflamvvdivqelkqqnprlvyvcdpvlgdkwdge
gsmyvpedllpvykekvvpladiitpnqfeaellsgrkihsqeealrvmdmlhsmgpdtv
vitssdlpspqgsnylivlgsqrrrnpvvmerirmdirkvdavfvgtgnlfaamllawth
khpnnlkvacektvstlhhvlqrtiqcakaqagegvrpspmqlelrmvqskrdiedpeiv
vqatvl

Timeline for d3fhya_:

• d3fhya_ first appeared in SCOPe 2.01
  
• d3fhya_ appears in SCOPe 2.04
  
• d3fhya_ appears in SCOPe 2.06
  
• d3fhya_ appears in the current release, SCOPe 2.08