Lineage for d3ffib_ (3ffi B:)

  1. Root: SCOPe 2.01
  2. 1054197Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)
  3. 1055706Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 1055707Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 1055873Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)
  6. 1055874Protein HIV-1 reverse transcriptase [56689] (3 species)
  7. 1055877Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (126 PDB entries)
    Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
  8. 1055935Domain d3ffib_: 3ffi B: [175756]
    automated match to d1c1cb_
    complexed with 3ob

Details for d3ffib_

PDB Entry: 3ffi (more details), 2.6 Å

PDB Description: HIV-1 RT with pyridone non-nucleoside inhibitor
PDB Compounds: (B:) RT p51

SCOPe Domain Sequences for d3ffib_:

Sequence, based on SEQRES records: (download)

>d3ffib_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyq

Sequence, based on observed residues (ATOM records): (download)

>d3ffib_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
stkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrky
taftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddl
yvgsdleigqhrtkieelrqhllrwglttwmgyelhpdkwtvqpivlpekdswtvndiqk
lvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyy
dpskdliaeiqkqgqgqwtyqiyqepfknlktgkyatndvkqlteavqkittesiviwgk
tpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

SCOPe Domain Coordinates for d3ffib_:

Click to download the PDB-style file with coordinates for d3ffib_.
(The format of our PDB-style files is described here.)

Timeline for d3ffib_: