SCOPe 2.03: Domain d3fdmc_: 3fdm C:

Lineage for d3fdmc_ (3fdm C:)

1. Root: SCOPe 2.03

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (29 PDB entries)

8. Domain d3fdmc_: 3fdm C: [175713]
   automated match to d1g5ja_
   complexed with edo

Details for d3fdmc_

PDB Entry: 3fdm, 2.26 Å

PDB Description: alpha/beta foldamer in complex with bcl-xl

PDB Compounds: (C:) apoptosis regulator bcl-x

SCOPe Domain Sequences for d3fdmc_:

Sequence; same for both SEQRES and ATOM records:

>d3fdmc_ f.1.4.1 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsqlhitpg
tayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmatylndh
lepwiqenggwdtfvelygnn

Timeline for d3fdmc_:

• d3fdmc_ first appeared in SCOPe 2.01
  
• d3fdmc_ appears in SCOPe 2.02
  
• d3fdmc_ appears in SCOPe 2.04
  
• d3fdmc_ appears in the current release, SCOPe 2.08