Lineage for d3f82a_ (3f82 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543916Protein Hepatocyte growth factor receptor, c-MET [103300] (1 species)
    PTK group; HGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2543917Species Human (Homo sapiens) [TaxId:9606] [103301] (57 PDB entries)
  8. 2543962Domain d3f82a_: 3f82 A: [175561]
    automated match to d1r0pa_
    complexed with 353

Details for d3f82a_

PDB Entry: 3f82 (more details), 2.5 Å

PDB Description: Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d3f82a_:

Sequence, based on SEQRES records: (download)

>d3f82a_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
lsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnr
itdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirneth
nptvkdligfglqvakgmkflaskkfvhrdlaarncmldekftvkvadfglardmydkef
dsvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditv
yllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyvhvna
tyvnvk

Sequence, based on observed residues (ATOM records): (download)

>d3f82a_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
lsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtllkihcavkslnrgevsq
fltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdlig
fglqvakgmkflaskkfvhrdlaarncmldekftvkvadfgklpvkwmaleslqtqkftt
ksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhp
kaemrpsfselvsrisaifstfigehyvhvnatyvnvk

SCOPe Domain Coordinates for d3f82a_:

Click to download the PDB-style file with coordinates for d3f82a_.
(The format of our PDB-style files is described here.)

Timeline for d3f82a_: