Lineage for d3f0vx_ (3f0v X:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2137244Family c.71.1.0: automated matches [191485] (1 protein)
    not a true family
  6. 2137245Protein automated matches [190777] (21 species)
    not a true protein
  7. 2137451Species Staphylococcus aureus [TaxId:273036] [188831] (12 PDB entries)
  8. 2137460Domain d3f0vx_: 3f0v X: [175386]
    automated match to d1ddra_
    complexed with 52v, ndp; mutant

Details for d3f0vx_

PDB Entry: 3f0v (more details), 2.35 Å

PDB Description: Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine
PDB Compounds: (X:) Trimethoprim-sensitive dihydrofolate reductase

SCOPe Domain Sequences for d3f0vx_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3f0vx_ c.71.1.0 (X:) automated matches {Staphylococcus aureus [TaxId: 273036]}

SCOPe Domain Coordinates for d3f0vx_:

Click to download the PDB-style file with coordinates for d3f0vx_.
(The format of our PDB-style files is described here.)

Timeline for d3f0vx_: