SCOPe 2.08: Domain d3f0rb1: 3f0r B:13-377

Lineage for d3f0rb1 (3f0r B:13-377)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)

8. Domain d3f0rb1: 3f0r B:13-377 [175380]
   Other proteins in same PDB: d3f0ra2, d3f0rb2
   automated match to d1t64a_
   complexed with k, tsn, zn

Details for d3f0rb1

PDB Entry: 3f0r, 2.54 Å

PDB Description: Crystal Structure Analysis of Human HDAC8 complexed with trichostatin A in a new monoclinic crystal form

PDB Compounds: (B:) Histone deacetylase 8

SCOPe Domain Sequences for d3f0rb1:

Sequence; same for both SEQRES and ATOM records:

>d3f0rb1 c.42.1.2 (B:13-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfht
daylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmck
vainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsft
skvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevy
qafnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlanta
rcwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgn
lkhvv

Timeline for d3f0rb1:

• d3f0rb1 first appeared in SCOPe 2.01, called d3f0rb_
  
• d3f0rb1 appears in SCOPe 2.07