SCOPe 2.08: Domain d3eztb_: 3ezt B:

Lineage for d3eztb_ (3ezt B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)

8. Domain d3eztb_: 3ezt B: [175344]
   automated match to d1t64a_
   complexed with b3n, bme, k, zn

Details for d3eztb_

PDB Entry: 3ezt, 2.85 Å

PDB Description: crystal structure analysis of human hdac8 d101e variant

PDB Compounds: (B:) Histone deacetylase 8

SCOPe Domain Sequences for d3eztb_:

Sequence, based on SEQRES records:

>d3eztb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgyecpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khvv

Sequence, based on observed residues (ATOM records):

>d3eztb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqdsieyglgyecpategifdyaaaiggatitaaqclidgmckvainwsgg
whhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvsl
hkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkav
vlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltg
vilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvv

Timeline for d3eztb_:

• d3eztb_ first appeared in SCOPe 2.01
  
• d3eztb_ appears in SCOPe 2.07