SCOPe 2.07: Domain d3et2b_: 3et2 B:

Lineage for d3et2b_ (3et2 B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48527] (34 PDB entries)

8. Domain d3et2b_: 3et2 B: [175210]
   automated match to d1gwxa_
   complexed with 1bo, et1

Details for d3et2b_

PDB Entry: 3et2, 2.24 Å

PDB Description: structure of ppardelta with 3-[5-methoxy-1-(4-methoxy- benzenesulfonyl)-1h-indol-3-yl]-propionic acid

PDB Compounds: (B:) Peroxisome proliferator-activated receptor delta

SCOPe Domain Sequences for d3et2b_:

Sequence, based on SEQRES records:

>d3et2b_ a.123.1.1 (B:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
adlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkqlv
nglppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifa
mlasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfi
aaiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvte
haqmmqrikktetetslhpllqeiykdmy

Sequence, based on observed residues (ATOM records):

>d3et2b_ a.123.1.1 (B:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
adlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkvng
lppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifaml
asivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaa
iilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvteha
qmmqrikktetetslhpllqeiykdmy

Timeline for d3et2b_:

• d3et2b_ first appeared in SCOPe 2.01
  
• d3et2b_ appears in SCOPe 2.06
  
• d3et2b_ appears in the current release, SCOPe 2.08