SCOPe 2.05: Domain d3et2a_: 3et2 A:

Lineage for d3et2a_ (3et2 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48527] (16 PDB entries)

8. Domain d3et2a_: 3et2 A: [175209]
   automated match to d1gwxa_
   complexed with 1bo, et1

Details for d3et2a_

PDB Entry: 3et2, 2.24 Å

PDB Description: structure of ppardelta with 3-[5-methoxy-1-(4-methoxy- benzenesulfonyl)-1h-indol-3-yl]-propionic acid

PDB Compounds: (A:) Peroxisome proliferator-activated receptor delta

SCOPe Domain Sequences for d3et2a_:

Sequence, based on SEQRES records:

>d3et2a_ a.123.1.1 (A:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
vadlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkql
vnglppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaif
amlasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalf
iaaiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvt
ehaqmmqrikktetetslhpllqeiykdm

Sequence, based on observed residues (ATOM records):

>d3et2a_ a.123.1.1 (A:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
vadlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwvng
lppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifaml
asivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaa
iilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvteha
qmmqrikktetetslhpllqeiykdm

Timeline for d3et2a_:

• d3et2a_ first appeared in SCOPe 2.01
  
• d3et2a_ appears in SCOPe 2.04
  
• d3et2a_ appears in SCOPe 2.06
  
• d3et2a_ appears in the current release, SCOPe 2.08