Lineage for d3eqrb_ (3eqr B:)

  1. Root: SCOPe 2.01
  2. 1013083Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1042202Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1042203Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1042269Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1042306Protein Activated CDC42 kinase 1, ACK1 [111200] (1 species)
    PTK group; Tck subfamily; non-membrane spanning protein tyrosine kinase
  7. 1042307Species Human (Homo sapiens) [TaxId:9606] [111201] (5 PDB entries)
    Uniprot Q07912 117-389
  8. 1042311Domain d3eqrb_: 3eqr B: [175163]
    automated match to d1u46b_
    complexed with cl, t74

Details for d3eqrb_

PDB Entry: 3eqr (more details), 2 Å

PDB Description: Crystal Structure of Ack1 with compound T74
PDB Compounds: (B:) Activated CDC42 kinase 1

SCOPe Domain Sequences for d3eqrb_:

Sequence, based on SEQRES records: (download)

>d3eqrb_ d.144.1.7 (B:) Activated CDC42 kinase 1, ACK1 {Human (Homo sapiens) [TaxId: 9606]}
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfaw
capeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedc
pqdiynvmvqcwahkpedrptfvalrdflleaqp

Sequence, based on observed residues (ATOM records): (download)

>d3eqrb_ d.144.1.7 (B:) Activated CDC42 kinase 1, ACK1 {Human (Homo sapiens) [TaxId: 9606]}
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmrkvpfawcap
eslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqd
iynvmvqcwahkpedrptfvalrdflleaqp

SCOPe Domain Coordinates for d3eqrb_:

Click to download the PDB-style file with coordinates for d3eqrb_.
(The format of our PDB-style files is described here.)

Timeline for d3eqrb_: