SCOPe 2.01: Domain d3ekka_: 3ekk A:

Lineage for d3ekka_ (3ekk A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin receptor [56162] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56163] (15 PDB entries)

8. Domain d3ekka_: 3ekk A: [175017]
   automated match to d1p14a_
   complexed with gs2

Details for d3ekka_

PDB Entry: 3ekk, 2.1 Å

PDB Description: insulin receptor kinase complexed with an inhibitor

PDB Compounds: (A:) Insulin receptor

SCOPe Domain Sequences for d3ekka_:

Sequence, based on SEQRES records:

>d3ekka_ d.144.1.7 (A:) Insulin receptor {Human (Homo sapiens) [TaxId: 9606]}
pssvyvpdewevsrekitllrelgqgsfgmvyegnardiikgeaetrvavktvnesaslr
erieflneasvmkgftchhvvrllgvvskgqptlvvmelmahgdlksylrslrpeaennp
grppptlqemiqmaaeiadgmaylnakkfvhrnlaarncmvahdftvkigdfgmtrdiye
tdyyrkggkgllpvrwmapeslkdgvfttssdmwsfgvvlweitslaeqpyqglsneqvl
kfvmdggyldqpdncpervtdlmrmcwqfnpnmrptfleivnllkddlhpsfpevsffhs
een

Sequence, based on observed residues (ATOM records):

>d3ekka_ d.144.1.7 (A:) Insulin receptor {Human (Homo sapiens) [TaxId: 9606]}
pssvyvpdewevsrekitllrelgqgsfgmvyegnardiikgeaetrvavktvnesaslr
erieflneasvmkgftchhvvrllgvvskgqptlvvmelmahgdlksylrslrpeaennp
grppptlqemiqmaaeiadgmaylnakkfvhrnlaarncmvahdftvkigdfllpvrwma
peslkdgvfttssdmwsfgvvlweitslaeqpyqglsneqvlkfvmdggyldqpdncper
vtdlmrmcwqfnpnmrptfleivnllkddlhpsfpevsffhseen

Timeline for d3ekka_:

• d3ekka_ is new in SCOPe 2.01-stable
  
• d3ekka_ appears in SCOPe 2.02
  
• d3ekka_ appears in the current release, SCOPe 2.08