SCOPe 2.08: Domain d3e7cb_: 3e7c B:

Lineage for d3e7cb_ (3e7c B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Glucocorticoid receptor [89140] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89141] (8 PDB entries)

8. Domain d3e7cb_: 3e7c B: [174714]
   automated match to d1m2za_
   complexed with 866, gol

Details for d3e7cb_

PDB Entry: 3e7c, 2.15 Å

PDB Description: glucocorticoid receptor lbd bound to gsk866

PDB Compounds: (B:) Glucocorticoid receptor

SCOPe Domain Sequences for d3e7cb_:

Sequence, based on SEQRES records:

>d3e7cb_ a.123.1.1 (B:) Glucocorticoid receptor {Human (Homo sapiens) [TaxId: 9606]}
lpqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgf
rnlhlddqmtllqyswmylmafalgwrsyrqssanllcfapdliineqrmtlpgmydqck
hmlyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivkr
egnssqnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipky
sngnikkllfhq

Sequence, based on observed residues (ATOM records):

>d3e7cb_ a.123.1.1 (B:) Glucocorticoid receptor {Human (Homo sapiens) [TaxId: 9606]}
lpqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgf
rnlhlddqmtllqyswmylmafalgwrsyrqanllcfapdliineqrmtlpgmydqckhm
lyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivksqn
wqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysngnikk
llfhq

Timeline for d3e7cb_:

• d3e7cb_ first appeared in SCOPe 2.01
  
• d3e7cb_ appears in SCOPe 2.07