Class d: Alpha and beta proteins (a+b) [53931] (388 folds) |
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) shares functional and structural similarities with the ATP-grasp fold and PIPK |
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins) members organized in the groups and subfamiles specified by the comments |
Protein Vascular endothelial growth factor receptor 2 (kdr) [56160] (1 species) PTK group; PDGFR/VEGFR subfamily; membrane spanning protein tyrosine kinase |
Species Human (Homo sapiens) [TaxId:9606] [56161] (25 PDB entries) |
Domain d3dtwa1: 3dtw A:818-1171 [174223] Other proteins in same PDB: d3dtwa2 automated match to d1vr2a_ complexed with a96 |
PDB Entry: 3dtw (more details), 2.9 Å
SCOPe Domain Sequences for d3dtwa1:
Sequence, based on SEQRES records: (download)
>d3dtwa1 d.144.1.7 (A:818-1171) Vascular endothelial growth factor receptor 2 (kdr) {Human (Homo sapiens) [TaxId: 9606]} erlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlkegaths ehralmselkilihighhlnvvnllgactkpggplmvitefckfgnlstylrskrnefvp ykvapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdf glardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgaspyp gvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllqan aqqd
>d3dtwa1 d.144.1.7 (A:818-1171) Vascular endothelial growth factor receptor 2 (kdr) {Human (Homo sapiens) [TaxId: 9606]} erlpydaskwefprdrlklgkplgrggqvieadafgidktcrtvavkmlkegathsehra lmselkilihighhlnvvnllgactkpggplmvitefckfgnlstylrskrnefvpykva pedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdflplk wmapetifdrvytiqsdvwsfgvllweifslgaspypgvkideefcrrlkegtrmrapdy ttpemyqtmldcwhgepsqrptfselvehlgnllqanaqqd
Timeline for d3dtwa1: