SCOPe 2.05: Domain d3dkoa_: 3dko A:

Lineage for d3dkoa_ (3dko A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)

8. Domain d3dkoa_: 3dko A: [174038]
   automated match to d1jpaa_
   protein/RNA complex; complexed with ihz

Details for d3dkoa_

PDB Entry: 3dko, 2 Å

PDB Description: complex between the kinase domain of human ephrin type-a receptor 7 (epha7) and inhibitor alw-ii-49-7

PDB Compounds: (A:) Ephrin type-A receptor 7

SCOPe Domain Sequences for d3dkoa_:

Sequence, based on SEQRES records:

>d3dkoa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tyidpetyedpnravhqfakeldascikiervigagefgevcsgrlklpgkrdvavaikt
lkvgytekqrrdflceasimgqfdhpnvvhlegvvtrgkpvmiviefmengaldaflrkh
dgqftviqlvgmlrgiaagmryladmgyvhrdlaarnilvnsnlvckvsdfglsrviedd
peavytttggkipvrwtapeaiqyrkftsasdvwsygivmwevmsygerpywdmsnqdvi
kaieegyrlpapmdcpaglhqlmldcwqkeraerpkfeqivgildkmirnpnsahh

Sequence, based on observed residues (ATOM records):

>d3dkoa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tyidpetyedpnravhqfakeldascikiervigaefgevcsgrlklpgkrdvavaiktl
kvgytekqrrdflceasimgqfdhpnvvhlegvvtrgkpvmiviefmengaldaflrkhd
gqftviqlvgmlrgiaagmryladmgyvhrdlaarnilvnsnlvckvsdfgpvrwtapea
iqyrkftsasdvwsygivmwevmsygerpywdmsnqdvikaieegyrlpapmdcpaglhq
lmldcwqkeraerpkfeqivgildkmirnpnsahh

Timeline for d3dkoa_:

• d3dkoa_ first appeared in SCOPe 2.01
  
• d3dkoa_ appears in SCOPe 2.04
  
• d3dkoa_ is called d3dkoa1 in SCOPe 2.06
  
• d3dkoa_ appears in the current release, SCOPe 2.08, called d3dkoa1