SCOPe 2.08: Domain d3dk7b_: 3dk7 B:

Lineage for d3dk7b_ (3dk7 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Abelsone tyrosine kinase (abl) [56166] (2 species)
   PTK group; Abl subfamily; non-membrane spanning protein tyrosine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56167] (16 PDB entries)

8. Domain d3dk7b_: 3dk7 B: [174028]
   automated match to d1opja_
   complexed with so4, sx7; mutant

Details for d3dk7b_

PDB Entry: 3dk7, 2.01 Å

PDB Description: crystal structure of mutant abl kinase domain in complex with small molecule fragment

PDB Compounds: (B:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3dk7b_:

Sequence, based on SEQRES records:

>d3dk7b_ d.144.1.7 (B:) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
dkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmke
ikhpnlvqllgvctreppfyiiiefmtygnlldylrecnrqevsavvllymatqissame
ylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesla
ynkfsiksdvwafgvllweiatygmspypgidpsqvyellekdyrmerpegcpekvyelm
racwqwnpsdrpsfaeihqafetmfqessisde

Sequence, based on observed residues (ATOM records):

>d3dk7b_ d.144.1.7 (B:) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
dkwemertditmkhklgggqygevyegvwkkysltvavktlmeveeflkeaavmkeikhp
nlvqllgvctreppfyiiiefmtygnlldylrecnrqevsavvllymatqissameylek
knfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkf
siksdvwafgvllweiatygmspypgidpsqvyellekdyrmerpegcpekvyelmracw
qwnpsdrpsfaeihqafetmfqessisde

Timeline for d3dk7b_:

• d3dk7b_ first appeared in SCOPe 2.01
  
• d3dk7b_ appears in SCOPe 2.07