SCOPe 2.08: Domain d3dk6a_: 3dk6 A:

Lineage for d3dk6a_ (3dk6 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Abelsone tyrosine kinase (abl) [56166] (2 species)
   PTK group; Abl subfamily; non-membrane spanning protein tyrosine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56167] (16 PDB entries)

8. Domain d3dk6a_: 3dk6 A: [174025]
   automated match to d1opjb_
   complexed with sx7; mutant

Details for d3dk6a_

PDB Entry: 3dk6, 2.02 Å

PDB Description: crystal structure of mutant abl kinase domain in complex with small molecule fragment

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3dk6a_:

Sequence, based on SEQRES records:

>d3dk6a_ d.144.1.7 (A:) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
dkwemertditmkhklgggqfgevyegvwkkysltvavktlkedtmeveeflkeaavmke
ikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqissame
ylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesla
ynkfsiksdvwafgvllweiatygmspypgidpsqvyellekdyrmerpegcpekvyelm
racwqwnpsdrpsfaeihqafetmfqessi

Sequence, based on observed residues (ATOM records):

>d3dk6a_ d.144.1.7 (A:) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
dkwemertditmkhklgqfgevyegvwkkysltvavktleveeflkeaavmkeikhpnlv
qllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqissameylekknf
ihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkfsik
sdvwafgvllweiatygmspypgidpsqvyellekdyrmerpegcpekvyelmracwqwn
psdrpsfaeihqafetmfqessi

Timeline for d3dk6a_:

• d3dk6a_ first appeared in SCOPe 2.01
  
• d3dk6a_ appears in SCOPe 2.07