SCOPe 2.07: Domain d3d94a_: 3d94 A:

Lineage for d3d94a_ (3d94 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (18 PDB entries)

8. Domain d3d94a_: 3d94 A: [173764]
   automated match to d1jqha_
   complexed with ca, d94

Details for d3d94a_

PDB Entry: 3d94, 2.3 Å

PDB Description: Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP

PDB Compounds: (A:) Insulin-like growth factor 1 receptor beta chain

SCOPe Domain Sequences for d3d94a_:

Sequence, based on SEQRES records:

>d3d94a_ d.144.1.7 (A:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
vyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvla
ppslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdy
yrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfv
megglldkpdncpdmllelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

Sequence, based on observed residues (ATOM records):

>d3d94a_ d.144.1.7 (A:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
vyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreri
eflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpslskmiqma
geiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgllpv
rwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkpdn
cpdmllelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

Timeline for d3d94a_:

• d3d94a_ first appeared in SCOPe 2.01
  
• d3d94a_ appears in SCOPe 2.06
  
• d3d94a_ appears in the current release, SCOPe 2.08