Lineage for d3d8ca1 (3d8c A:11-349)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2070014Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2070786Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2070961Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein)
  6. 2070962Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species)
  7. 2070963Species Human (Homo sapiens) [TaxId:9606] [82196] (29 PDB entries)
  8. 2070967Domain d3d8ca1: 3d8c A:11-349 [173751]
    Other proteins in same PDB: d3d8ca2
    automated match to d1iz3a_
    complexed with akg, gol, so4, zn; mutant

Details for d3d8ca1

PDB Entry: 3d8c (more details), 2.1 Å

PDB Description: Factor inhibiting HIF-1 alpha D201G mutant in complex with ZN(II), alpha-ketoglutarate and HIF-1 alpha 19mer
PDB Compounds: (A:) hypoxia-inducible factor 1 alpha inhibitor

SCOPe Domain Sequences for d3d8ca1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3d8ca1 b.82.2.6 (A:11-349) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3d8ca1:

Click to download the PDB-style file with coordinates for d3d8ca1.
(The format of our PDB-style files is described here.)

Timeline for d3d8ca1: