SCOPe 2.07: Domain d3d23b1: 3d23 B:1-300

Lineage for d3d23b1 (3d23 B:1-300)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
   contains an extra alpha-helical domain

7. Species Human coronavirus [TaxId:443239] [188597] (6 PDB entries)

8. Domain d3d23b1: 3d23 B:1-300 [173628]
   Other proteins in same PDB: d3d23a2, d3d23b2
   automated match to d1uj1b_
   protein/RNA complex

Details for d3d23b1

PDB Entry: 3d23, 2.5 Å

PDB Description: main protease of hcov-hku1

PDB Compounds: (B:) 3C-like proteinase

SCOPe Domain Sequences for d3d23b1:

Sequence; same for both SEQRES and ATOM records:

>d3d23b1 b.47.1.4 (B:1-300) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Human coronavirus [TaxId: 443239]}
sgivkmvsptskiepcivsvtygsmtlnglwlddkvycprhvicsssnmnepdysallcr
vtlgdftimsgrmsltvvsyqmqgcqlvltvslqnpytpkytfgnvkpgetftvlaayng
rpqgafhvtmrssytikgsflcgscgsvgyvltgdsvkfvymhqlelstgchtgtdftgn
fygpyrdaqvvqlpvkdyvqtvnviawlyaailnncawfvqndvcstedfnvwamangfs
qvkadlvldalasmtgvsietllaaikrlymgfqgrqilgsctfedelapsdvyqqlagv

Timeline for d3d23b1:

• d3d23b1 first appeared in SCOPe 2.01, called d3d23b_
  
• d3d23b1 appears in SCOPe 2.06
  
• d3d23b1 appears in the current release, SCOPe 2.08