Lineage for d3d23a1 (3d23 A:1-300)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057856Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 protein domains)
  6. 2057913Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (6 species)
    contains an extra alpha-helical domain
  7. 2057919Species Human coronavirus [TaxId:443239] [188597] (3 PDB entries)
  8. 2057923Domain d3d23a1: 3d23 A:1-300 [173627]
    Other proteins in same PDB: d3d23a2, d3d23b2
    automated match to d1uj1b_
    protein/RNA complex

Details for d3d23a1

PDB Entry: 3d23 (more details), 2.5 Å

PDB Description: main protease of hcov-hku1
PDB Compounds: (A:) 3C-like proteinase

SCOPe Domain Sequences for d3d23a1:

Sequence, based on SEQRES records: (download)

>d3d23a1 b.47.1.4 (A:1-300) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Human coronavirus [TaxId: 443239]}
sgivkmvsptskiepcivsvtygsmtlnglwlddkvycprhvicsssnmnepdysallcr
vtlgdftimsgrmsltvvsyqmqgcqlvltvslqnpytpkytfgnvkpgetftvlaayng
rpqgafhvtmrssytikgsflcgscgsvgyvltgdsvkfvymhqlelstgchtgtdftgn
fygpyrdaqvvqlpvkdyvqtvnviawlyaailnncawfvqndvcstedfnvwamangfs
qvkadlvldalasmtgvsietllaaikrlymgfqgrqilgsctfedelapsdvyqqlagv

Sequence, based on observed residues (ATOM records): (download)

>d3d23a1 b.47.1.4 (A:1-300) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Human coronavirus [TaxId: 443239]}
sgivkmvsptskiepcivsvtygsmtlnglwlddkvycprhvicsmnepdysallcrvtl
gdftimsgrmsltvvsyqmqgcqlvltvslqnpytpkytfgnvkpgetftvlaayngrpq
gafhvtmrssytikgsflcgscgsvgyvltgdsvkfvymhqlelstgchtgtdftgnfyg
pyrdaqvvqlpvkdyvqtvnviawlyaailnncawfvqndvcstedfnvwamangfsqvk
adlvldalasmtgvsietllaaikrlymgfqgrqilgsctfedelapsdvyqqlagv

SCOPe Domain Coordinates for d3d23a1:

Click to download the PDB-style file with coordinates for d3d23a1.
(The format of our PDB-style files is described here.)

Timeline for d3d23a1: